CRFCN0254E

Configuration directory variable not set in registry. Changes will not be saved. Do you want to continue?

The configuration directory variable values in the registry is modified.
Changes in the application configuration tool is not saved if Yes option is selected. But you can continue to use the tool and run the application from this tool. The application configuration tool is closed if No option is selected.
Try to reinstall the product. If the problem persists contact support.